Genzyme, one of the world’s leading biotechnology companies, is dedicated to making a major positive impact on the lives of those afflicted with serious diseases. Since 1981, the company has grown from a small start-up company in Boston to a diversified enterprise with more than 10,000 employees worldwide and 2007 revenues of $3.8 billion. In early 2007, Genzyme performed a supply chain risk assessment. Based on the results, they decided to start the Serial Number Management System (SNMS) initiative to implement global serialization and track & trace. Since Genzyme trades in both Europe and the U.S., it needed a solution that would not only enable EPCglobal EPC Information Services (EPCIS) events but also meet California pedigree requirements. Axway’s Track & Trace, with its modular components, is being deployed to address Genzyme’s specific needs, providing a total solution for pedigree and track & trace.